I can tell you from experience that anything that stimulates dopamine production in your brain is bad news. I could not drink cofee for 2 years after a couple of years clubbing in London.
I can tell you coke is £50 for a few hours of fun, but it's not worth it. Turns you into an instant twat.
I don't do any of that crap now, but I'm happy to have the odd redbull during a game of poker.
All things in moderation. What comes up must come down.
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